The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) is seeking a contractor to provide a resource of preclinical and non-clinical services to advance the development of Topical microbicides (TM) and biomedical prevention (BP). There is a critical need to promote discovery and transition of new strategies into clinical trials. This NIAID-sponsored contract focuses on promoting the development of strategies containing TM/BP as a means to address the NIAID and Division of AIDS (DAIDS) priority of controlling and preventing the HIV/AIDS epidemic worldwide. This contract will provide pre-clinical and non-clinical development services of TM/BP products essential for advancement to clinical testing and for supporting activities required for IND and NDE applications to the FDA. TM/BP products for development services will be provided by or through the Project Officer and will be identified through NIAID-funded grants and contracts, the private sector, or other sources.