UPGRADE: Spinning Disk System: Dual Camera, Piezo Z, Software and Workstation
This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. This solicitation number is NICHD-17-194 and is issued as a Request for Quotation (RFQ). The solicitation/contract will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2005-95. The North American Industry Classification (NAICS) Code is 333314 and the business size standard is 1000 employees. However, this solicitation is not set aside for small business. This acquisition is being conducted using Simplified Acquisition Procedures in accordance with FAR Part 13. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) intend to contract on a sole source basis with Carl Zeiss Microscopy, LLC, One Zeiss Drive, Thornwood 10594 to procure Upgrades for Existing Carl Zeiss Spinning Disk System: Dual Camera, Piezo Z, Software and Workstation with following features:
Required for Dual Cam
423638-9340-000 1 EA Second Camera Base CSU-X1
426118-9000-000 1 EA Camera adapter 60N 1.0x long with TL 1x
446434-0011-000 1 EA Beam splitter FT 510 f/ CSU-X1
446437-0011-000 1 EA Beam splitter FT 560 f/ CSU-X1
423638-9330-000 1 EA Holder f/ second. beam splitter / CSU-X1
000000-1761-634 1 EA Leg supports for camera base CSU-X1
410830-1703-000 2 EA C13440-20CU-KIT Flash4.0 V3 sCMOS Camera
410830-1704-000 2 EA CAMRA-1007-000-KIT Flash4.0 v3 Cam Link
410830-1701-000 2 EA CAMRA-4303-000 Trigger Cable Flash 4.0
423638-9250-000 1 EA Camera adapter c-mount for CSU-X1
Piezo z upgrade
400100-9021-000 1 EA Trigger board µCon HS (PCI xPress)
432927-9041-000 1 EA Signal Distribution Box Rev. 2
432339-9000-000 1 EA Stage Attachment Z PIEZO WSB 500
432339-9010-000 1 EA Controller Z PIEZO WSB 500
432339-9020-000 1 EA Control wheel Z PIEZO WSB 500
000000-1356-074 1 EA Cable for stage top frame Z PIEZO
431018-0000-000 1 EA Z Drive Mot Extended Travel 13mm
432339-9050-000 1 EA Stage insert Z PIEZO WSB Heating inserts
432339-9030-000 1 EA Stage insert Z-PIEZO WSB Universal
Computer and software
410203-9910-000 1 EA Workstation High-End ZEISS 55A R2 GPGPU
410138-1068-230 1 EA ZEN Module Upgrade 3D VisArt to 3DxI HWL
410136-1019-110 1 EA ZEN Module Physiology Hardware Lic. Key
410136-1002-120 1 EA ZEN Module Macro Environment HWL
Installation & Shipping
000000-0239-500 1 EA Installation
Estimated Shipping 1 CHG
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Intramural Research Program (IRP) conducts biomedical research and training related to diabetes mellitus; endocrine, bone, and metabolic diseases; digestive diseases, including liver diseases and nutritional disorders; and kidney, urologic, and hematologic diseases. Intramural research is conducted in the Institute's laboratories and clinical facilities in Bethesda, Maryland and in Phoenix, Arizona. There are currently 19 Laboratories and Branches (i.e. 19 departments with different focus areas) in the NIDDK Intermural Research Program.
Most if not all these areas of research, either occasionally or on an ongoing basis, require advanced fluorescence microscopy, including confocal microscopy, as the basis of a quantitative assay or to qualitatively complement other assays. The Spinning Disk Confocal Microscope (SDC) was originally purchased to satisfy such a need. Spinning disk confocal microscopy has been, and remains the best technology to image live cultured cells, labeled with fluorescent markers, over time. The LERB SDC thus provides a useful technology resource for other NIDDK departments outside LERB.
Although the LERB SDC is useful to some in its current state, it requires upgrades to keep pace with technology and users' wishes for experiments. It is not nearly as sensitive nor as fast as what is currently available on the market, and several NIDDK researchers have not been able to pursue experiments that would greatly advance their studies. Because this SDC has hardware-based autofocus and the capability to turn lasers on/off within a few microseconds, whereas other SDCs in NIDDK do not have these features, it is the most cost-effective to upgrade this SDC to current technology, to answer researchers' experimental requirements.
All tasks need to be compatible with existing hardware and functionality of this Spinning Disk Confocal Microscope. Replacement of the existing CCD camera (NIH keeps the old camera) with dual 3rd-generation CMOS cameras:
Low light sensitivity and background noise reduction at least as good as the Hamamatsu Flash 4.0 v3.
Pixel size when using a 100x lens should be 50-80 nm in the sample space.
Software supports simultaneous or sequential imaging with the two cameras.
Images from the two cameras can be aligned in a few minutes by trained NIH staff after changing the dichroic between the two cameras.
Timing of camera acquisition is synchronized with laser on/off on a sub-millisecond time scale. Addition of piezo stage insert to enable much faster movements in between image acquisitions during z-stacks, with sub-msec synchronization with lasers and cameras.
The offeror must include a completed copy of the provision of FAR Clause 52.212-3, Offeror Representations and Certifications - Commercial Items with its offer. The provisions of FAR Clause 52.212-1 Instructions to Offerors - Commercial Items; FAR Clause 52.212-2, Evaluation - Commercial Items; FAR Clause 52.212-4, Contract Terms and Conditions - Commercial Items; and FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items - Deviation for Simplified Acquisitions applies to this acquisition. The offeror must include their Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. The clauses are available in full text at http://www.acquisition.gov/far/. Interested vendors capable of furnishing the government with the all the products and or services specified in this synopsis should submit a copy of their quotation to the below address or via email to verne.griffin@nih.gov. Offers must also be accompanied by descriptive literature, delivery timeframe, warranties and/or other information that demonstrates that the offer meets all the foregoing requirements. Quotations will be by August 24, 2017 before 10:00 am EST. via email or postal mail. The quotation must reference "Solicitation number" NICHD-17-194. Quotations sent by postal mail or other mailing services must be submitted to the following address: Eunice Kennedy Shriver National Institute of Child Health and Human Development - 6710B Rockledge Drive, Room MSC 1159A, Bethesda, MD 20892. Note: Fed Ex/Ups/other courier use 20817. Attention: Verne Griffin, by the date and time mentioned above.
Any questions must be sent via email to verne.griffin@mail.nih.gov and must include solicitation# NICHD-17-194 in the subject line of email.
Faxed copies/responses will not be accepted. Email solicitations not accepted.
Note: In order to receive an award, contractor must be registered and have valid certification for all awards in the SAM database @www.sam.gov.
Verne Griffin, Email verne.griffin@nih.gov
