The National Institute on Drug Abuse (NIDA) intends to solicit proposals from qualified organizations having in-house capability to develop a valid and reliable, standardized instrument that measures the propensity to and severity of drug addiction. The instrument is expected to provide transformational, scientific, technical, and practical utility for addiction research through its capacity to quantify the likelihood of becoming addicted (propensity) and an objective measure of the extent to which addiction manifests once developed (severity).