Pathology Services
Typical tasks to be performed will include, but not be limited to, the following:
Pathology peer review of toxicology studies conducted by another contractor
Necropsy and pathology support for in vivo studies (TRAVEL WILL BE REQUIRED)
Immunohistochemical localization and semi-quantitation of molecular targets/biomarkers of
interest from in vivo and in vitro studies
Human (and animal, if applicable) tissue binding specificity studies of therapeutic antibodies
per FDA guidelines (contractor prepares a study protocol)
Processing of human biopsies/samples into slides, stain (routine, immunohistochemical or
specialty), histologic evaluation and interpretation of results (no diagnosis)
Storage of pathology materials from pharmacology and toxicology studies including slides,
blocks, fixed tissues and frozen specimens
Storage of pathology materials from other sources such as studies at an outside
investigators lab
Establishing a repository database that has a format compatible with seamless migration of
data to a variety of other databases
Maintaining and promptly updating the repository database
