Notice of Intent to Sole Source-IPA software
The US Army Medical Research Acquisition Activity (USAMRAA), Fort Detrick, Maryland intends to negotiate on a sole source basis with Wiagen, 27220 Turnberrt Ln Valencia CA 91355 as they are the only responsible source capable of meeting the following MEC's for the Ingenuity Paythways Analysis software Part Number 830017:
1.1. Minimum Essential Characteristics
The Ingenuity Pathways Analysis shall:
1.1.1. Be compatible with current data that has been collected and processed by IPA for several on-going research projects governed by BTNN.
1.1.2. Provide a graphical user interface and allow data to be saved and exported to text and images.
1.1.3. Dynamically create and draw interaction networks and pathways.
1.1.4. Automatically curate databases from published research and literature citations.
1.1.5. Shows data origin and provide validity of constructed networks.
1.1.6. Use the mammalian databases and be compatible with all biological molecules and types of annotations or interactions: proteins and peptides, lipids, small molecules, all types of genomic data (microRNA, DNA, RNA, genetic polymorphisms), diseases genomic positioning, RNA-Seq based and next generation sequencing experiments, and drugs.
1.1.7. Must be compatible with data generated with the following vendor databases/identifiers without requesting the user to convert IDs before entering data.
1.1.7.1. Compatible identifiers must include: Affimetrix (Exon/GeneExpression,3' IVT Expression), Affimetrix SNP ID (genotyping), Agilent and Applied Biosystems (gene and miRNA), CAS Registry, Codelink, dbSNP IDs (including Illumina genotyping arrays with dbSNP IDs),EntrezGene, Ensembl, GenBank, GenPept, GI Number, HUGO Data base, Gene Symbol, Human Metabolome Database (HMDB),KEGG, Illumina (whole genome and miRNA), the International Protein Index, miRbase, PubChem CID, RefSeq, UCSC Human Isoform IDs, Unigene, and Uniprot/Swiss Prot Accession
1.1.7.2. Compatible Species must include: Rat, mouse, human, and canine
1.1.8. Provide synonym resolution.
1.1.9. Provide contextual information in interaction mapping (e.g. organ, cell type resolution).
1.1.10. Support predictive analytics based on data.
1.1.11. Provide orthologue mapping across species.
1.1.12. Provide the following relationship types relationship types: binding, chemical reactions, direct regulation, expression, synthesis, protein modification, regulation, any user-defined relationship (e.g. expandable per the user's needs).
1.1.13. Provide a knowledge database of drug effects.
1.1.14. Allow users to modify layouts at will or construct pathways manually and visualize all pathways per user's specifications (e.g. with or without cellular localization).
1.1.15. Import data from Excel, XML, binary, tab delimited, formats.
1.1.16. Export pathways or selected entities as image, HTML, XML, Excel, txt formats.
1.1.17. Support and allows automated data curation based on Affimetrix arrays, Uniprot or IPI based proteomics assays, Pubmed IDs, gene/protein/lipid names, and GEO GDS format.
1.1.18. Conduct pathway convergence, Pearson correlations, gene set enrichment analysis, sub-network analysis.
1.1.19. Have the ability to filter data by genes, type, organism, relationships, direct or indirect interactions (with a user-defined number of steps between entities), sub-classes.
1.1.20. Allow customized annotations such that the user to generate interactions based on novel, unpublished research findings.
1.1.21. Provide secure storage, import, and export of raw and analyzed data as well as images and detailed reports for publication.
1.1.22. Provide a 5-user license that allows sharing and securing data among lab members, per the users' needs.
1.1.23. Provide a web based application.
1.1.24. Maintain curation such that annotation are as accurate as possible.
1.1.25. Provide web-based subscription.
There are no set-aside restrictions for this requirement. This notice of intent is not a request for competitive proposals and no solicitation document exists for this requirement. However, parties interested in responding to this notice shall submit technical data, including cost, sufficient to determine capability in providing the same product. All capability statements received by closing of this notification of this synopsis will be considered by the Government. A determination by the Government not to compete based on responses to this notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement.
The NAICS for this requirement is 541511 and PSC 7030
This announcement fulfills the synopsis requirements under FAR 5.102(a)(6) and 5.203(a).
If a vendor challenges the basis of this requirement, please email product capability statements (formats for submission: PDF, MS Word, or MS Excel) to Kasey Carroll at kasey.l.carroll.civ@mail.mil. Closing date for challenges is no later than 10:00 AM ET on 23 January 2019. No phone calls will be accepted.
Kasey Carroll, Contract Specialist, Phone 301-619-2799, Email kasey.l.carroll.civ@mail.mil
