Musculoskeletal and Skin Tissue Engineering and Regenerative Medicine
# Purpose. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) solicits Accelerating Research Translation (ART) applications in musculoskeletal and skin tissue engineering and regenerative medicine (TE/RM). The ART awards intend to offer revision support (formerly referred to as a competing supplement) to active NIAMS R01, P01 and P50 (parent) grants for conducting large animal pre-clinical studies with the potential to immediately lead to human trials in musculoskeletal and skin TE/RM. These studies will 1) provide data required for Phase I/II human clinical trials in musculoskeletal and skin TE/RM, 2) demonstrate efficacy of a TE/RM therapy in musculoskeletal and skin TE/RM, or 3) develop pre-clinical large animal models that will have the potential to immediately lead TE/RM research into Phase I/II clinical trials. Early stage translational studies using small animals such as rodent and rabbit are not responsive to this FOA.
