Bill and Melinda Gates Foundation RFP for Novel Artemisinin Manufacturing Technologies
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The goal of this project is to develop novel approaches through the proof of concept stage for the manufacturing of artemisinin and/or its precursors as a starting material or intermediate to prepare artemisinin-based active pharmaceutical ingredients. These approaches should demonstrate the potential (with a high probability of success) to meet aggressive cost targets when being practiced at commercial scale. It is anticipated (but not guaranteed) that successful awardees will be requested to submit a further proposal for additional development work, scale-up to pilot scale and generation of the necessary materials (e.g. cell banks) and technology transfer packages to enable manufacturing at multiple existing manufacturing facilities. It is likely that multiple responders will require partnering to meet the RFP objectives and to help facilitate this, the Foundation will be scheduling two virtual proposer events. Interested parties are requested to complete and submit a six page Concept Memorandum by the deadlines outlined below and in the attached RFP.
