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ALTERNATIVE ROUTES OF ADMINISTRATION and/or ALTERNATIVE FORMULATIONS FOR INFLUENZA IMMUNIZATION


District Of Columbia, United States
Government : Federal
RFP
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REQUEST FOR INFORMATION

******** RESEARCH AND *********** AND EMERGING ******** DIVISION *************

TITLE: ROUTES OF ADMINISTRATION and/or ************ FOR INFLUENZA ************
RFI No: RFI-19-BARDA-ALT-FLU-************-0001

1.0 Description

1.1 The Influenza and Emerging ******** Division (IEIDD), in support of the Biomedical ******** Research and *********** Authority (BARDA), is seeking information regarding ways an interested contractor could assist the U.S. Government (USG) with route of administration and/or ************ approaches for pandemic/pre-pandemic influenza vaccines. The intent is to improve the concept of operation for a mass vaccination and/or accelerate the time to reach protective immune response.


1.2 THIS IS A REQUEST FOR INFORMATION (RFI) ONLY


IEIDD is issuing this RFI solely for information and planning purposes - it does NOT constitute a Request for Proposal (RFP), a promise to issue a RFP, or a commitment to issue any type of solicitation in the future. This RFI does not commit the USG to contract any supply or service whatsoever. At this time, IEIDD is not seeking *********** proposals and will not accept or review unsolicited proposals received.


The USG will not pay for any information or administrative costs incurred in response to this RFI; all costs associated with responding to this RFI will be solely at the interested party's expense. Submission is voluntary and is not required to propose to subsequent solicitation on this topic (if any.)


If IEIDD chooses to release a solicitation in the future, it will be synopsized on the Federal Business Opportunities (FedBizOpps) website and the Office of the Assistant Secretary for Preparedness & Response (ASPR) website at ----. It is the responsibility of the potential respondee to monitor these sites for additional information pertaining to any potential requirement.


2.0 Background


Within the USG, the Department of Health and Human Services (HHS), Assistant Secretary for Preparedness and Response (ASPR), the Biomedical ******** Research and *********** Authority (BARDA) is tasked with protecting the civilian population by providing leadership in research, ***********, acquisition, deployment, and use of effective medical countermeasures to treat the adverse health effects resulting from intentional exposure to chemical, , radiological, and nuclear (CBRN) threat agents, and natural exposure(s) to pandemic influenza and emerging ********.


Prevention of disease caused by seasonal and novel influenza strains of pandemic potential continues to be a public health challenge. Traditional parenteral vaccinations are the primary medical intervention for prevention of infections with these viruses. In an effort to improve preparedness capabilities and the 2017 Pandemic Influenza Plan (PIP) calling for the first doses of vaccines to be available at 12 weeks, (---- ) the USG is seeking to gather information from developers for Routes of Administration for pandemic/pre-pandemic...

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